Two preliminary human clinical anti-aging trials have proven to be a success. The stem cell therapy has yieled results that show reversal of systems associated with frailty due to age. The results suggest that this treatment is not only safe but also highly effective in combating the key factors in aging. Scientists have been working on a variety of methods to achieve anti-aging targets. Recent discoveries include a protein that restores hair and improves fitness. This particular trial deals with anti-aging stem cell treatment.

Mesenchymal stem cells or MSCs are being used for treating over a dozen different types of pathological conditions like cancer and heart disease. This new MSC treatment aims to reduce the effects of frailty on senior citizens. According to reports, this is the first treatment of its kind to come close to the coveted FDA approval stage.

The treatment involves extracting human mesenchymal stem cells from adult donor bone marrow and using a single infusion into patients with an average age of 76. Phase 1 and Phase 2 of the preliminary human clinical trials have revealed that there are no adverse effects on the patient’s health.

The first trial involved 15 frail patients who received a single infusion collection from the bone marrow of donors between the ages of 20 and 45 years old. All of the patients demonstrated an improved overall quality of life, fitness outcomes, and tumor necrosis factor levels after six months.

The second trial was a double blind study with a placebo group. No adverse effects were repoted and researchers noted that the physical improvements that those who received an infusion were “remarkable.”

An expanded Phase 2b clinical trial is the next stage which will involve 120 patients in more than 10 locations. A final randomized Phase 3 trial will be conducted after that and the treatment might subsequently receive final public approval.

Filed in Medical.. Source: newatlas